Caspase 8 (Cleaved-Asp384) Antibody

Catalog No.

L0167

Size

50 µg

Price

325.00€

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Product details

Applications

WB ELISA

Source

Rabbit

Reactivity

H

MW (kDa)

47 and 55 kDa

Target Modification

Cleaved

Immunogen

The antiserum was produced against synthesized peptide derived from human Caspase 8.

Immunogen Range

335-384

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Specificity

Caspase 8 (Cleaved-Asp384) Antibody detects endogenous levels of fragment of activated Caspase 8 resulting from cleavage adjacent to Asp384.

Gene ID

841

Swiss-Prot No.

Q14790

OMIM No.

211980/601763/607271

Unigene No.

Hs.599762

NCBI Gene Symbol

CASP8

Synonyms

Apoptotic cysteine protease; Apoptotic protease Mch-5; CAP4; Caspase-8 precursor; FADD-homologous ICE/CED-3- like protease; FADD-like ICE; FLICE; ICE-like apoptotic protease 5; ICE8; MACH; MCH5; MORT1-associated CED-3 homolog

Storage / Stability

Stable at -20°C for at least 1 year.

Physical Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Concentration

1 mg/ml

Properties

If you buy Antibodies supplied by Assay Biotech they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Description

Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.

French translation

anticorps