Calcium Sensing Receptor (Phospho-Thr888) Antibody

Catalog No.

A0828-A

Size

100 µg

Price

425.00€

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Product details

Applications

WB IF ELISA

Source

Rabbit

Reactivity

H, M, R

MW (kDa)

120 kDa

Target Modification

Phospho

Modification Sites

H:T888 M:T888 R:T888

Immunogen

The antiserum was produced against synthesized peptide derived from human Calcium Sensing Receptor around the phosphorylation site of Thr888.

Immunogen Range

854-903

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Specificity

Calcium Sensing Receptor (Phospho-Thr888) Antibody detects endogenous levels of Calcium Sensing Receptor only when phosphorylated at Thr888.

Gene ID

846

Swiss-Prot No.

P41180

OMIM No.

145980/146200/239200/601199

Unigene No.

Hs.435615

NCBI Gene Symbol

CASR

Synonyms

Extracellular calcium-sensing receptor; CaSR; Parathyroid Cell calcium-sensing receptor; PCaR1; CASR; GPRC2A; PCAR1

Storage / Stability

Stable at -20°C for at least 1 year.

Physical Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Concentration

1 mg/ml

Properties

If you buy Antibodies supplied by Assay Biotech they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Description

The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

French translation

anticorps