Caspase 8 (Phospho-Ser347) Antibody

Catalog No.

A0059

Size

50 µg

Price

325.00€

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Product details

Applications

WB IHC ELISA

Source

Rabbit

Reactivity

H, R

MW (kDa)

55 kDa

Target Modification

Phospho

Modification Sites

H:S347 R:S349

Immunogen

The antiserum was produced against synthesized peptide derived from human Caspase 8 around the phosphorylation site of Ser347.

Immunogen Range

313-362

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Specificity

Caspase 8 (Phospho-Ser347) Antibody detects endogenous levels of Caspase 8 only when phosphorylated at Ser347.

Gene ID

841

Swiss-Prot No.

Q14790

OMIM No.

211980/601763/607271

Unigene No.

Hs.599762

NCBI Gene Symbol

CASP8

Synonyms

Apoptotic cysteine protease; Apoptotic protease Mch-5; CAP4; Caspase-8 precursor; FADD-homologous ICE/CED-3- like protease; FADD-like ICE; FLICE; ICE-like apoptotic protease 5; ICE8; MACH; MCH5; MORT1-associated CED-3 homolog

Storage / Stability

Stable at -20°C for at least 1 year.

Physical Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Concentration

1 mg/ml

Properties

If you buy Antibodies supplied by Assay Biotech they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Description

Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.

French translation

anticorps