The antiserum was produced against synthesized peptide derived from human COT around the phosphorylation site of Thr290.
Immunogen Range
256-305
Purification
The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Specificity
COT (Phospho-Thr290) Antibody detects endogenous levels of COT only when phosphorylated at Thr290.
Gene ID
1326
Swiss-Prot No.
P41279
OMIM No.
191195
Unigene No.
Hs.432453
NCBI Gene Symbol
MAP3K8
Synonyms
C-COT; COT proto-oncogene serine/threonine-protein kinase; Cancer Osaka thyroid oncogene; M3K8; MAP3K8; Mitogen-activated protein kinase kinase kinase 8; TPL-2; TPL2; Tpl2; Tumor progression locus 2; kinase Cot
Storage / Stability
Stable at -20°C for at least 1 year.
Physical Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Clonality
Polyclonal
Concentration
1 mg/ml
Properties
If you buy Antibodies supplied by Assay Biotech they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.