PDGF Receptor beta (Phospho-Tyr751) Antibody

Catalog No.

A7194

Size

50 µg

Price

325.00€

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Product details

Applications

IHC ELISA

Source

Rabbit

Reactivity

H, M, R

MW (kDa)

123 kDa

Target Modification

Phospho

Modification Sites

H:Y751 M:Y750 R:Y750

Immunogen

The antiserum was produced against synthesized peptide derived from human PDGF Receptor beta around the phosphorylation site of Tyr751.

Immunogen Range

718-767

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Specificity

PDGF Receptor beta (Phospho-Tyr751) Antibody detects endogenous levels of PDGF Receptor beta only when phosphorylated at Tyr751.

Gene ID

5159

Swiss-Prot No.

P09619

OMIM No.

131440/173410

Unigene No.

Hs.509067

NCBI Gene Symbol

PDGFRB

Synonyms

CD140b; kinase PDGFR-beta; PDGF-R-beta; PDGFR; PDGFR-beta; PGFRB; platelet-derived growth factor receptor, beta polypeptide

Storage / Stability

Stable at -20°C for at least 1 year.

Physical Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Concentration

1 mg/ml

Properties

If you buy Antibodies supplied by Assay Biotech they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Description

The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

French translation

anticorps