Thyroid Hormone Receptor beta Antibody

Catalog No.

C0346

Size

50 µg

Price

325.00€

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Product details

Applications

WB IHC ELISA

Source

Rabbit

Reactivity

H, M, R

MW (kDa)

52 kDa

Target Modification

Unmodified/Total

Immunogen

The antiserum was produced against synthesized peptide derived from human Thyroid Hormone Receptor beta.

Immunogen Range

11-60

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Specificity

Thyroid Hormone Receptor beta Antibody detects endogenous levels of total Thyroid Hormone Receptor beta protein.

Gene ID

7068

Swiss-Prot No.

P10828

OMIM No.

145650/188570/190160/274300

Unigene No.

Hs.187861

NCBI Gene Symbol

THRB

Synonyms

C-ERBA-BETA; ERBA2; NR1A2; THB1; THR1

Storage / Stability

Stable at -20°C for at least 1 year.

Physical Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Concentration

1 mg/ml

Tissue

thyroid

Properties

If you buy Antibodies supplied by Assay Biotech they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Description

Hormone releasing factors and releasing hormones are  signaling molecules produced by glands in multicellular organisms. The glands that secrete Luteinizing hormones LHRG and LH, FSH comprise the endocrine signaling system. The term growth hormone releasing hormone GHRH is sometimes extended to include chemicals produced by cells that affect the same cell (autocrine or intracrine signaling) or nearby cells (paracrine signaling). Human recombinant LHRG and GHRH are produced in E. coli or in yeast cells.The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

French translation

anticorps