Leptin Receptor Antibody

Catalog No.

B8265-A

Size

100 µg

Price

425.00€

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Product details

Applications

WB ELISA

Source

Rabbit

Reactivity

H, M

MW (kDa)

132 kDa

Target Modification

Unmodified/Total

Immunogen

The antiserum was produced against synthesized peptide derived from human Leptin Receptor.

Immunogen Range

1107-1156

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Specificity

Leptin Receptor Antibody detects endogenous levels of total Leptin Receptor protein.

Gene ID

3953

Swiss-Prot No.

P48357

OMIM No.

601007

Unigene No.

Hs.723178/HS.23581

NCBI Gene Symbol

LEPR

Synonyms

B219; CD295; DB; HuB219; LEP-R; leptin receptor; OB receptor; OB-R; OBR

Storage / Stability

Stable at -20°C for at least 1 year.

Physical Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Concentration

1 mg/ml

Properties

If you buy Antibodies supplied by Assay Biotech they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Gene

Human or mouse Leptin (from Greek λεπτός leptos, "thin") the "satiety hormone", is a hormone made by adipose cells that helps to regulate energy balance by inhibiting hunger. Leptin is opposed by the actions of the hormone ghrelin, the "hunger hormone". Both hormones act on receptors in the arcuate nucleus of the hypothalamus to regulate appetite to achieve energy homeostasis. ELISA kits and peptides and antibodies are available.

Description

The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

French translation

anticorps